Monday, November 20, 2017
Bioresource Development For Industry

Group Leader

 Dr. M. A. Ghauri

Dy Chief Scientist

Team Members:

 

 

 

 

The areas of research employing extremophilic microorganisms are as under:

  • Microbial Biodiversity and Systematics
  • Biotechnology of Extremophiles
  • Extremozymes
  • Gene Mining

 

Biodiversity is an attribute of an area and specifically refers to the varieties within and among living organisms, assemblage of the living organisms, biotic communities and biotic processes, whether naturally occurring or modified by humans. Interest in the biodiversity of extreme environments has grown over the past several years for several reasons, including the theory that such conditions were predominant on the young planet Earth. Thus early life forms may have consisted of organisms adapted to such environments, the so called extremophiles. The scientific benefits of microbial diversity research include a better understanding of the role and function of microbial communities in various terrestrial, marine, and aquatic environments. The economic and strategic benefits are the discovery of microorganisms for exploitation in biotechnological processes for new antibiotic and therapeutic agents, probiotics, novel fine chemicals, enzymes and polymers for use in industrial and scientific applications, for bioremediation of polluted environments, and bioleaching and recovery of minerals, as well as preparedness against exotic and emerging pathogens of humans, animals, and plants. Bioresource is a country’s most valuable source that can be exploited in many ways.

 

In this area of research, we survey potential sites for the acquisition of extremophilic microorganisms and then apply them in various projects being carried out at Industrial Biotechnology Division for academic and commercial benefit. Preliminary characterisation of the enriched cultures was carried out for various growth affecting parameters viz., nutritional requirements, temperature, pH etc. Bacterial diversity is determined by16S rDNA sequence analysis.

 

          

                                                                       

Facilities

  • Forior Transform Infra Red Spectrophotometer (FTIR)

  • Field emission scanning electron microscope (FESEM)
  • Surface area and porosimetry system
  • F T-NIR
  • Double beam UV-visible spectrophotometer
  • High Performance Liquid Chromatography, FPLC
  • Potento Gravimetric  STAT
  • Gas Chromatography Mass Spectrometer, muffle furnace, and automated fermentors (1-300L) 

     

Support 

  • HEC: Bioleaching of metals from their ores. Gene mining studies of extremophiles. Strain improvement for cellulose production.Biopesticides using mutant of B.thuringiensis.   
  • MoST: Biodesulphurization of fossil fuels.Cloning of cellulase gene for ethanol production. Synthesis & applications of metal nanoparticles.
  • PSF: Development of cephalosporin C producing strain. Cloning of raw starch digesting α-amylase from Bacillus specie & its expression in E coli
  • PTCL: Production & characterization of α-amylase.
   
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