Tuesday, October 27, 2020

Dr. Shahid M. Baig

shahidbaig@nibge.org , shahid_baig2002@yahoo.com

Dy Chief Scientist

Work Phone: +92 41 9201316-20/Ext 241
Fax Phone: +92-41-9201472
Cell/Direct Phone: +92 3009730304
Dr. Shahid M. Baig




  • M.Sc. (Biology), Quaid-i-Azam University Islamabad, 1984.
  • M.Phil. (Physiology of Reproduction), Quaid-i-Azam University Islamabad,1986.
  • Ph.D. (Human Molecular Genetics), Quaid-i-Azam University, Islamabad, 1996.
  • Postdoc. (Human Molecular Genetics), King Saud University, Saudi Arabia, 2003


Research Interests:

  • Molecular Genetics of  β-thalassemia
  • Prenatal Diagnosis
  • Gene Mapping of Monogenic Disorders in Pakistani Population
  • Establishments of Carrier Screening Tests


Research Publications:

  • Hussain, M.S., Baig, S.M., Neumann, S., Peche, V.S., Nürnberg, G., Tariq, M., Jameel, M., Naeem, T., Fatima, A., Malik, N.A., Ahmad, I., Altmüller, J., Frommolt, P., Thiele, H., Höhne, W., Yigit, G., Wollnik, B., Nürnberg, P., Noegel, A.A. 2013. CDK6 associates with the centrosome during mitosis and is mutated in a large Pakistani family with primary microcephaly. HMG (In press: HMG-2013-D-00658R1). Impact Factor:7.692
  • Farooq, M., Nakai, H., Fujimoto, A., Fujikawa, H., Kjaer, K.W., Baig, S.M., Shimomura, Y. 2013. Characterization of a novel missense mutation in the prodomain of GDF5, which underlies brachydactyly type C and mild Grebe type chondrodysplasia in a large Pakistani family. Hum Genet, Jun 29, [Epub ahead of print]. Impact Factor: 4.633
  • Hussain, M.S., Bakhtiar, S.M. Noegel, Farooq, M., Anjum. I., Noegel, A.A., Nürnberg, P. Tommerup, N., Kjaer, K.W., Baig, S.M., Hansen, L. 2013. Genetic heterogeneity in Pakistani microcephaly families. Clin Genet. 83(5), 446-451.. Impact Factor: 3.94
  • Mansuy-Aubert, V., Zhou, Q.L., Xie, X., Gong, Z., Huang, J.Y., Khan, A.R., Aubert, G., Candelaria, K., Thomas, S., Shin, D.J., Booth, S., Baig, S.M., Bilal, A., Hwang, D., Zhang, H., Lovell-Badge, R., Smith, S.R., Awan, F.R.  and Jiang, Z.Y. 2013. Imbalance between Neutrophil Elastase and Its Inhibitor a1-Antitrypsin Alters Inflammation, Insulin Sensitivity and Energy Expenditure in Obesity. Cell Metabolism, 17:534-548. Impact Factor: 14.619
  • Hansen, L., Rehman, SU., Tawamie, H., Murakami, Y., Buchert, R., Schaffer, S., Muhammad, S., Nöthen, M.M., Maeda, Y., Wang, Y., Aigner, M., Reis, A., Kinoshita, T., Tommerup, N., Baig, S.M., Jamra, R.A. (2013). Hypomorphic mutations in the GPI-anchor remodeling gene PGAP2 cause autosomal recessive intellectual disability with elevated alkaline phosphatase. AJHG, 92(4):575-583. Impact Factor: 11.02
  • Cui, C.Y., Klar, J., Frojmark, A.S., Baig, S.M., Dahl, N. 2013. Frizzled6 deficiency disrupts the differentiation process of nail development. J Invest Dermatol. Feb 25. doi: 10.1038/jid.2013.84. [Epub ahead of print]. Impact Factor: 6.139
  • Khan, T.N., Klar, J., Ali, Z., Khan, F., Baig, S.M. and Dahl N. 2013. Cenani-Lenz syndrome restricted to limb and kidney anomalies associated with a novel LRP4 missense mutation. Eur J Med Genet, May 7, doi:pil:S1769-7212(13)00091-8. 10.1016/ejmg.2013.04.07. [Epub ahead of print]. Impact Factor: 1.685
  • Iqbal, Z. Aleem, A. Baig S.M. et al. 2013. Sensitive detection of pre-existing BCR-ABL kinase domain mutations in CD34+ cells of newly diagnosed chronic-phase chronic myeloid leukaemia patients is associated with imatinib resistance: implications in the post imatinib era.  PLoS One. 2013;8(2):e55717. doi:10.1371/journal.pone. Epub ahead of print Feb 8. Impact Factor: 3.370.
  • Sultan, N., Baig, S.M, Sheikh, M.A., Jamil, A., Rahman, S.. 2013. Autosomal recessive Retinitis pigmentosa is associated with missense mutation in CRB1 in a consanguineous Pakistani family. PJLSS (In Press, 201-PJLSS-13). Impact Factor: 0
  • Khan, T.N., Klar, J., Nawaz, S., Jameel, M., Tariq, M., Malik, N.A., Baig, S.M. and Dahl N. 2012. Novel missense mutation in the RSPO4 gene in congenital hyponychia and evidence for polymorphic initiation codon (p.M11). BMC Medical Genetics, Dec 13 doi:10.1186/147-2350-13-120. Impact Factor: 2.536
  • Tariq, M., Azhar, A., Baig, S.M., Dahl, N., Klar, J. 2012.  A novel mutation in the Lipase H gene underlies autosomal recessive hypotrichosis and woolly hair. Scientific Reports, 2:730. Oct 12, doi: 10.1038/srep00730. Impact Factor: 2.92
  • Azhar, A., Tariq, M., Baig, S.M., Dahl, N., Klar, J. 2012. A novel mutation in Lysophosphatidic Acid Receptor 6 gene in autosomal recessive hypotrichosis and evidence for a founder effect. Eur J Dermatol 22(4):464-466.Impact Factor: 2.526
  • Baig, S.M., Sabih, D., Rahim, K., Azhar, A., Tariq, M., Hussain, M.S., Baig, UR., Qureshi, J.A., Baig, SA., Bakhtiar, S. M. 2012. β-Thalsssemia in Pakistan: a pilot program on prenatal diagnosis in Multan. J Pediatr Hematol Oncol 34(2):90-92. Impact Factor: 1.159
  • Nawaz, S., Tariq, M., Ahmad, I., Malik, N.A., Baig, S.M., Dahl, N., Klar, J. 2012. Nonbullous congenital erythrodeerma associated with homozygosity for a novel missense mutation in an ATP binding domain of ABCA12. Eur J Dermatol 22(2):178-181. Impact Factor: 2.526
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