Friday, December 04, 2020
Profile

Dr. Shahid Mansoor

shahidmansoor7@gmail.com

Fellow Pakistan Academy of Sciences
Chief Scientist
Sitara-e-Imtiaz (S.I)

Work Phone: +92-41-2651471
Fax Phone: +92-41-2651472
Cell/Direct Phone: +92-41-2651917
Dr. Shahid Mansoor

Academic Qualification

  • Doctor of Philosophy (Ph.D)-1999- Department of Virus Research, The John Innes Centre Norwich, U.K and the degree awarded by Department of Biological Sciences, University of East Anglia.
  • Master of Science in Biochemistry (M.Sc.)-1987- University of Karachi, Department of Biochemistry, University of Karachi with first class second position. Thesis titled " Physical isolation and characterisation of drug resistance plasmids".
  • Bachelor of Science in Biochemistry(B.Sc. Hon). 1986- University of Karachi, Department of Biochemistry, University of Karachi with first class second position. Major subjects studied include physiology, biochemistry, chemistry, microbiology, molecular biology and neurochemistry.

Service Record

  • Research fellow at National Institute for Biotechnology and Genetic Engineering, Faisalabad from February, 1988 to March, 1989.
  • Scientific Officer at National Institute for Biotechnology and Genetic Engineering, Faisalabad in 1stApril, 1989.
  • Senior Scientific Officer at National Institute for Biotechnology and Genetic Engineering, Faisalabad from December, 1994.
  • Principal Scientific Officer at National Institute for Biotechnology and Genetic Engineering, Faisalabad from December, 2002.
  • Head Agricultural Biotechnology Division at National Institute for Biotechnology and Genetic Engineering, Faisalabad from 1st March, 2006 to 3rd July, 2013.
  • Deputy Chief Scientific at National Institute for Biotechnology and Genetic Engineering, Faisalabad from December, 2012.
  • Director at National Institute for Biotechnology and Genetic Engineering, Faisalabad from 4th July, 2013todate.
  • Chief Scientist at National Institute for Biotechnology and Genetic Engineering, Faisalabad from December 2019 to date.
  • Visiting Scientist at the Department of Health Effect ENEA CRE Casaccia, Rome, Italy from Jan. 1990 to March 1991. The field of study was Thermobiology and Immunology under the supervision of Professor Gino Doria and Marcello Spano.
  • Visiting Scientist at Department of Virus Research, John Innes Centre under Dr. Peter G. Markham and Dr. John Stanley on cotton leaf curl virus from Pakistan from January 1993 to May 1993.
  • Royal Society UK, Fellowship 2000, One year sponsored by The Royal Society, UK in the laboratory of Prof. David, Baulcombe, Sainsbury Laboratory, John Innes Centre, Norwich, UK on "Manipulation of Rx gene for resistance against geminiviruses and characterization of begomoviruses and small circular DNA molecules associated with cotton leaf curl virus and Ageratum yellow vein virus in Pakistan.
  • Fulbright Scholar 2011-12, one year at Plant Genome Mapping Laboratory, University of Georgia, Athens, under the leadership of Prof. Andrew Paterson on genomics of cotton.

 

Honours and awards (National and International)

  • First class position in B.Sc. (Hons) Biochemistry, University of Karachi
  • First class position in M.Sc. Biochemistry, University of Karachi
  • Awarded Royal Society UK Fellowship
  • Award of Sitara-e-Imtiaz on the 62ndindependence day of 14th August’ 2009, by President of Pakistan in recognition of meritorious services and achievements.
  • HEC Outstanding Performance Award (Research Paper 2005-6)
  • HEC Outstanding Performance Award ((Research Paper 2011)
  • Research Productivity Award for PCST for the last ten years
  • HEC Distinguished National Professor
  • Fellow Pakistan Academy of Sciences (PAS)
  • Member Prime Minister’s Task Force on Science and Technology
  • Member Rice Research and Development Board, Government of Punjab

 

Research Project Leader

  • Founding member and group leader of Plant Molecular Virology and Gene Silencing, NIBGE.
  • Principal investigator “Use of Molecular methods for the Evaluation of Diversity of Cotton Leaf Curl and other whitefly transmitted Geminiviruses which are potential threat to Cotton Crop. Funded by MINFAL/ADB. Rs. 5.358 million (1995-1997) (P.I. Dr. Shahid Mansoor)
  • Principal investigator Development of genetically-engineered broad based resistance against cotton leaf curl and tomato leaf curl virus. Research project funded by International Foundation for Science (IFS) Sweden12,000US$.
  • Principal investigatorUse of RNA interference for genetically-engineered male sterile tomato plants for production of hybrid tomato ALP (PARC)(Rs. 03.225 million).
  • Principal investigatorICGEB collaborative CRP/Pak 03-02 “Use of RNA interference for engineering resistance against economically-important plant DNA viruses”US$ 35,000.
  • Principal investigator PAK-US collaborative project “Understating on control of plant virus disease complexes in Pakistan”.(US$ 0.142 million) Funded by Ministry of Science and Technology (MoST).
  • Principal investigator“Use of RNA Interference Technology for Engineering Broad-spectrum Resistance Against Economically Important Geminiviruses”(Rs.27.00 million), Funded by Ministry of Science and Technology (MoST).
  • Principal investigator Research grants to active scientists/ technologists of Pakistan PSF (1.00 million) 
  • Principal investigator “Control of mealy bug in Pakistan”. Rs. 26.474 Million Funded by Ministry of Food Agriculture and Livestock (MinFAL)
  • Principal investigator “Development of transgenic cotton with multiple genes resistant to cotton leaf curl virus” Rs. 16.299 Millionfunded by Punjab Agricultural Research Board (PARB).
  • Principal investigator “Development of gene constructs and genetically-engineered germplasm resources/commercial genotypes resistant to cotton leaf curl disease and/or its insect vector” US$ 498000 funded by USDA (ICARDA).
  • Principal investigator Pak-USA collaborative project “Characterization and utilization of Gossypiumarboreum as source of resistance against begomoviruses that are threat to Pakistan and USA” (US$ 0.1702 million)funded by Higher Education Commission, Pakistan.
  • Principal investigator Management of whitefly by integrated strategies and development of resistant cotton germplasm through genetic engineering by PARB  (23 million)
  • Principal investigator Development of commercial cotton varieties expressing Cry1Ac and Cry2Ab proteins for effective control of Lepidopteran insectsfunded by HEC under technology development fund (13.257 Million).
  • Principal investigator Developing virus resistance and improving cold storage of potato by silencing eIF4e/eIF(iso)4e and VInv using a transgene-free CRISPR/Cas9 mediated genome editing (19.179 million), Funded by Higher Education Commission, Pakistan.
  • Principal investigator, Development and application of genomic selection in foreign and local cattle breeds for improvement in dairy related traits, funded by ALP, PARC (4.95 million).
  • Principal investigator, Establishing innovative technology platforms for fast-track development of elite livestock and crops for food and nutritional security, a collaborative project between NIBGE, ICCBS and QAU at a cost of Rs. 909 million funded by Ministry of Science and Technology.

 

 

Research interests

  • Molecular characterization of economically important geminiviruses on cotton, tomato, chillies, okra, cucurbits, beans and other crops
  • Characterization  of satellites and satellite-like molecules associated with geminiviruses
  • Development of molecular diagnostic tools for geminivirus detection
  • Characterization of geminivirus gene function
  • Geminivirus-host interactions and identification of host proteins that interact with geminivirus-encoded proteins
  • Characterization of whitefly biotypes, influence on virus transmission efficiency and their distribution in Pakistan
  • Use of RNA interference and other genetic engineering tools for development of genetically-engineered resistance against geminiviruses
  • Characterization of natural sources of resistance against geminiviruses
  • Use of RNAi for development of male sterility
  • Use of RNA interference and other technologies for engineered resistance against whiteflies
  • Next generation sequencing and genome characterization of cotton, whiteflies and livestock
  • Genome editing for creating novel traits in cotton and other crops
  • Use of genomic selection in enhancing genetic gain in crops and livestock by use of genomic selection
  • Biotechnology as a tool for socio-economic development of the country

 

PUBLICATIONS

 

Total I.F = more than 934.866                                 Total Citation: more than 10832

                                               

Books

Edited a book 2003 titled “Genome characterization of whitefly-transmitted geminiviruses of cotton and development of virus-resistant plants through genetic engineering and conventional breeding. Technical Paper No. 22, Common Fund for Commodities, The Netherlands.

 

Book Chapters

 

  • Ahmed N, I. Amin and S. Mansoor.Cotton Leaf Curl Disease (Geminiviridae). Encyclopedia of Virology (2020).
  • BLPatil, S Chakraborty, H Czosnek, E Robert, LGilbertson, J Legg, SMansoor, JN Castillo, RZNaqvi, SURahman, FMZerbini. Plant Resistance to Geminiviruses. Encyclopedia of Virology (2020).
  • Mansoor S. et al. Dictionary of Cotton. Published by ICAC. 
  • Mansoor S, I. Amin, R W. Briddon. 2011. Geminiviral diseases of cotton. In Cotton Stress Physiology Book. National Cotton Council, USA.
  • Imran Amin, M. Ilyas, S. Mansoor, R.W. Briddon and M. Saeed (2009). “Role of DNA satellites in geminivirus disease complexes”. Emerging geminivirial diseases and their management” Editors: P.Sharma, R.K. Gaur and M. Ikegami, 2010 Nova Science Publishers, Inc., (ISBN 978-1—61668-620-8 Suite 1600, Hauooauge, NY 1788 USA
  •  Muhammad Ilyas, I, Amin, S. Mansoor, R. W. Briddon and M. Saeed (2009). ”Challenges for transgenic resistance to control geminiviral diseases”. Emerging geminiviral diseases and their management by Nova Science Publishers, Inc., (ISBN 978-1-61668-620-8 Suite 1600, Hauooauge, NY 1788 USA.
  •  Mansoor S, Amin I. and Briddon RW. 2008. "Cotton leaf curl disease ". Encyclopedia of Virology, vols # 5 (B.W.J. Mahy and M.H.V. Van Regenmortel, Editors) pp 563-569 Oxford: Elsevier
  • Briddon RW and Mansoor S. 2008. "DNA beta satellites of begomoviruses". Encyclopedia of Virology, Elsevier Ltd, Oxford, OX5 1GB, U.K  pp 314-321 Oxford: Elsevier
  • Mansoor, S., S. H. Khan, M. Hussain, A. Bashir, M. Saeed, Y. Zafar, J. Stanley, R. Briddon, P. G. Markhamand K. A. Malik (1999). DNA variants among Pakistan isolates of cotton leaf curl virus. In proceeding of Regional Consultation on Insecticide Resistance Management in Cotton, June 28 to July 1, 1999, Multan, Pakistan, pp. 261-276.
  • Zafar, Y., A. Bashir, S. Mansoor,  M. Saeed, S. Asad,  N. A. Saeed, S. Shabnam, M.  Iqbal,  and K. A. Malik (1996). Molecular and biological characterization of cotton leaf curl virus and development of virus-resistant cotton through genetic engineering. Proceeding of First National Biotechnology meeting by Center for Agriculture Biochemistry and Biotechnology (CABB), University of Agriculture, Faisalabad.
  • Malik, K.A., S. Mansoor, Nasir A. Saeed, S. Asad, Y. Zafar John Stanley and P.Markham (1995). Development of CLCV-resistant cotton varieties through genetic engineering proceedings of National Seminar on Strategies for Increasing Production April 26-27, 1995, Agri. Dept. pp 39-41 Published by Punjab Agriculture Department.
  • Mansoor, S., J. Stanley, K. A. Malik, and P.G. Markham (1995). Molecular characterisation of a geminivirus associated with cotton leaf curl disease in Pakistan. Proceeding of International Symposium on Biotechnology for sustainable development. Eds. K. A. Malik, A. Nasim and A.M. Khalid ISBN: 969-8189-01-7.

 

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